Why is my USB mouse disconnecting and reconnecting randomly and often?

Problem

My mouse will reconnect/disconnect (will even hear the sounds from Windows), and the light on the bottom of the mouse will turn off/turn on as it starts working again. It really sucks to be playing a game (and happens on desktop as well) for the mouse to just die out for a few seconds and come back. Sometimes it will not happen for days and other times it will do it two or more times within 15 seconds. I tried two different wired mice, tried multiple USB ports (on the front of the computer, back of the computer, used a USB hub and plugged in a card that connects to the USB connectors on the motherboard and adds a few USB ports to the back of the computer, and I also bought a USB 2.0 PCI card and that did not help). Nothing else seems to reconnect like this, my USB keyboard has never once cut out like the mouse does and neither have any of the other devices I have connected (webcam, USB hub, various devices sometimes connected through USB cables, and IR receiver for windows Media Cente…